Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions.
<p>Medical research is the systematic, rigorous investigation of health-related problems in order to generate new knowledge or confirm existing knowledge, with the potential benefit of evidence-based medical practice and policy guidance.</p> <br/> <p>The validity of the findi...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Malawi Medical Journal
2017
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| _version_ | 1797103121273454592 |
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| author | Mbotwa, J Singini, I Mukaka, M |
| author_facet | Mbotwa, J Singini, I Mukaka, M |
| author_sort | Mbotwa, J |
| collection | OXFORD |
| description | <p>Medical research is the systematic, rigorous investigation of health-related problems in order to generate new knowledge or confirm existing knowledge, with the potential benefit of evidence-based medical practice and policy guidance.</p> <br/> <p>The validity of the findings from medical research requires a thorough process from design, to data collection and data analysis.1 However, the methods that researchers use during analyses are often unsuitable for the designs used during study conduct. Researchers are supposed to choose the study designs at the time of protocol development, before any investigation is carried out. Different study designs have different strengths and weaknesses.2 The selected design should be the most appropriate design to answer the objectives of a study. This decision is crucial, as study design reflects directly on the hypothesis of interest. Sample size and other design aspects of the study are aimed at achieving valid conclusions of a trial or study. It is therefore important to strive for compatibility between study design and analysis plan.</p> |
| first_indexed | 2024-03-07T06:15:35Z |
| format | Journal article |
| id | oxford-uuid:f0fa639d-9db1-4504-b0c2-a82edf4aa519 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:15:35Z |
| publishDate | 2017 |
| publisher | Malawi Medical Journal |
| record_format | dspace |
| spelling | oxford-uuid:f0fa639d-9db1-4504-b0c2-a82edf4aa5192022-03-27T11:52:16ZDiscrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f0fa639d-9db1-4504-b0c2-a82edf4aa519EnglishSymplectic Elements at OxfordMalawi Medical Journal2017Mbotwa, JSingini, IMukaka, M<p>Medical research is the systematic, rigorous investigation of health-related problems in order to generate new knowledge or confirm existing knowledge, with the potential benefit of evidence-based medical practice and policy guidance.</p> <br/> <p>The validity of the findings from medical research requires a thorough process from design, to data collection and data analysis.1 However, the methods that researchers use during analyses are often unsuitable for the designs used during study conduct. Researchers are supposed to choose the study designs at the time of protocol development, before any investigation is carried out. Different study designs have different strengths and weaknesses.2 The selected design should be the most appropriate design to answer the objectives of a study. This decision is crucial, as study design reflects directly on the hypothesis of interest. Sample size and other design aspects of the study are aimed at achieving valid conclusions of a trial or study. It is therefore important to strive for compatibility between study design and analysis plan.</p> |
| spellingShingle | Mbotwa, J Singini, I Mukaka, M Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions. |
| title | Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions. |
| title_full | Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions. |
| title_fullStr | Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions. |
| title_full_unstemmed | Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions. |
| title_short | Discrepancy between statistical analysis method and study design in medical research: Examples, implications, and potential solutions. |
| title_sort | discrepancy between statistical analysis method and study design in medical research examples implications and potential solutions |
| work_keys_str_mv | AT mbotwaj discrepancybetweenstatisticalanalysismethodandstudydesigninmedicalresearchexamplesimplicationsandpotentialsolutions AT singinii discrepancybetweenstatisticalanalysismethodandstudydesigninmedicalresearchexamplesimplicationsandpotentialsolutions AT mukakam discrepancybetweenstatisticalanalysismethodandstudydesigninmedicalresearchexamplesimplicationsandpotentialsolutions |