Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.

Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.

Metastasis results from a sequence of selective events often involving interactions with elements of the tumor-specific physiological microenvironment. The low-serum component of this microenvironment confers increased motility and invasion in breast cancer cells by activating the Na+/H+ exchanger i...

Full description

Bibliographic Details
Main Authors: Cardone, R, Bagorda, A, Bellizzi, A, Busco, G, Guerra, L, Paradiso, A, Casavola, V, Zaccolo, M, Reshkin, S
Format: Journal article
Language:English
Published: 2005

Similar Items

Similar Items