Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.

Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.

Metastasis results from a sequence of selective events often involving interactions with elements of the tumor-specific physiological microenvironment. The low-serum component of this microenvironment confers increased motility and invasion in breast cancer cells by activating the Na+/H+ exchanger i...

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Detalles Bibliográficos
Autores principales: Cardone, R, Bagorda, A, Bellizzi, A, Busco, G, Guerra, L, Paradiso, A, Casavola, V, Zaccolo, M, Reshkin, S
Formato: Journal article
Lenguaje:English
Publicado: 2005

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