A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands.

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands.

Drosophila has three membrane-tethered epidermal growth factor (EGF)-like proteins: Spitz, Gurken and Keren. Spitz and Gurken have been genetically confirmed to activate the EGF receptor, but Keren is uncharacterized. Spitz is activated by regulated intracellular translocation and cleavage by the tr...

書目詳細資料
Main Authors:	Urban, S, Lee, JR, Freeman, M
格式:	Journal article
語言:	English
出版:	2002

相似書籍

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases.
由: Urban, S, et al.
出版: (2001)

An Arabidopsis Rhomboid homolog is an intramembrane protease in plants.
由: Kanaoka, M, et al.
出版: (2005)

Mechanism and function of the intramembrane-cleaving protease rhomboid
由: Lemberg, M, et al.
出版: (2005)

Mechanism and function of the intramembrane-cleaving protease rhomboid
由: Lemberg, M, et al.
出版: (2005)

Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.
由: Lemberg, M, et al.
出版: (2005)

Rhomboids and intramembrane proteolysis
由: Freeman, M, et al.
出版: (2005)

A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling.
由: Wasserman, J, et al.
出版: (2000)

Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain.
由: Urban, S, et al.
出版: (2003)

Rhomboid intramembrane proteases: from substrate specificity and mechanism to biological function
由: Strisovsky, K, et al.
出版: (2009)

Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases.
由: Lemberg, M, et al.
出版: (2007)

Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases.
由: Pierrat, O, et al.
出版: (2011)

Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids.
由: Urban, S, et al.
出版: (2002)

Mammalian EGF receptor activation by the rhomboid protease RHBDL2.
由: Adrain, C, et al.
出版: (2011)

Intramembrane proteolysis by rhomboids: catalytic mechanisms and regulatory principles.
由: Vinothkumar, K, et al.
出版: (2013)

Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα
由: Wunderle, L, et al.
出版: (2016)

Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates.
由: Strisovsky, K, et al.
出版: (2009)

Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.
由: Lee, JR, et al.
出版: (2001)

Rhomboids: 7 years of a new protease family.
由: Freeman, M
出版: (2009)

Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity
由: Henry Sawczyc, et al.
出版: (2024-08-01)

Rhomboid proteases and their biological functions.
由: Freeman, M
出版: (2008)

Mitochondrial membrane remodelling regulated by a conserved rhomboid protease.
由: McQuibban, G, et al.
出版: (2003)

Rhomboid proteases and growth factor signaling
由: Freeman, M
出版: (2009)

GlyGly-CTERM and rhombosortase: a C-terminal protein processing signal in a many-to-one pairing with a rhomboid family intramembrane serine protease.
由: Daniel H Haft, et al.
出版: (2011-01-01)

Substrates and physiological functions of secretase rhomboids proteases
由: Freeman, M, et al.
出版: (2016)

Bacterial rhomboid proteases mediate quality control of orphan membrane proteins
由: Liu, G, et al.
出版: (2020)

Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics
由: Syed M Moin, et al.
出版: (2012-11-01)

Signaling Functions of Intramembrane Aspartyl-Proteases
由: Alkmini A. Papadopoulou, et al.
出版: (2020-12-01)

Rhomboid proteases in human disease: mechanisms and future prospects
由: Düsterhöft, S, et al.
出版: (2017)

Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboids.
由: Lohi, O, et al.
出版: (2004)

Proteolysis within the membrane: rhomboids revealed.
由: Freeman, M
出版: (2004)

Intramembrane-cleaving proteases (I-CLiPs) /
由: Hooper, Nigel M., et al.
出版: (2007)

Identification of an archaeal presenilin-like intramembrane protease.
由: Celia Torres-Arancivia, et al.
出版: (2010-01-01)

A Subset of Membrane-Altering Agents and γ-Secretase Modulators Provoke Nonsubstrate Cleavage by Rhomboid Proteases
由: Siniša Urban, et al.
出版: (2014-09-01)

Rhomboids.
由: Freeman, M
出版: (2003)

The structural basis for catalysis and substrate specificity of a rhomboid protease.
由: Vinothkumar, K, et al.
出版: (2010)

Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function.
由: McQuibban, G, et al.
出版: (2006)

Intramembrane proteolysis controls diverse signalling pathways throughout evolution.
由: Urban, S, et al.
出版: (2002)

Expression and characterization of Drosophila signal peptide peptidase-like (sppL), a gene that encodes an intramembrane protease.
由: David J Casso, et al.
出版: (2012-01-01)

Intramembrane protease RasP boosts protein production in Bacillus
由: Jolanda Neef, et al.
出版: (2017-04-01)

Structure of rhomboid protease in complex with β-lactam inhibitors defines the S2' cavity.
由: Vinothkumar, K, et al.
出版: (2013)