Bis(1,3-dihydroxy-isopropyl)amine (BDI) as an AB(4) dendritic building block: rapid synthesis of a second generation dendrimer

Bis(1,3-dihydroxy-isopropyl)amine (BDI)1, a symmetrical AB4 dendritic building block, is developed into two diamine linkers in which the nitrogen is more nucleophilic. The four primary alcohols in BDI undergo Michael reactions with t-butyl acrylate. Branch cells of this rare multiplicity allow the r...

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Main Authors: Scott, D, Krulle, T, Finn, M, Fleet, G
格式: Journal article
語言:English
出版: 2000