Inhibition of Bruton's tyrosine kinase regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation

Inhibition of Bruton's tyrosine kinase regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation

Background and Purpose Currently there are limited medicines available for the treatment of metabolic inflammation in diseases such as obesity and type 2 diabetes (T2D). Although initially associated with B‐ells, Bruton's tyrosine kinase (BTK) is present in a wide variety of cells including mon...

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Бібліографічні деталі
Автори: Purvis, GSD, Collino, M, Aranda-Tavio, H, Chiazza, F, O'Riordan, CE, Zeboudj, L, Mohammad, S, Collotta, D, Verta, R, Guisot, NES, Bunyard, P, Yaqoob, MM, Greaves, DR, Thiemermann, C
Формат: Journal article
Мова:English
Опубліковано: Wiley 2020

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