Tethered aminohydroxylation: synthesis of the β-amino acid of microsclerodermins A and B.

The utility of the tethered aminohydroxylation (TA) has been demonstrated by synthesis of the complex β-amino acid residue of microsclerodermins A and B. The TA provided a regio- and stereoselective functionalization of a complex homoallylic alcohol. The route includes late-stage introduction of the...

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Autori principali: Pullin, R, Rathi, A, Melikhova, E, Winter, C, Thompson, A, Donohoe, T
Natura: Journal article
Lingua:English
Pubblicazione: 2013