Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure.
High-affinity histamine-binding proteins (HBPs) were discovered in the saliva of Rhipicephalus appendiculatus ticks. Their ability to outcompete histamine receptors indicates that they suppress inflammation during blood feeding. The crystal structure of a histamine-bound HBP, determined at 1.25 A re...
Main Authors: | Paesen, G, Adams, P, Harlos, K, Nuttall, P, Stuart, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1999
|
Similar Items
-
Histamine - Binding proteins in tick saliva
by: Paesen, G, et al.
Published: (1998) -
Tick histamine-binding proteins: lipocalins with a second binding cavity.
by: Paesen, G, et al.
Published: (2000) -
A high affinity serotonin- and histamine-binding lipocalin from tick saliva.
by: Sangamnatdej, S, et al.
Published: (2002) -
A tick protein with a modified Kunitz fold inhibits human tryptase.
by: Paesen, G, et al.
Published: (2007) -
Arthropod-derived histamine-binding protein prevents murine allergic asthma.
by: Couillin, I, et al.
Published: (2004)