Estimating meiotic gene conversion rates from population genetic data.

Estimating meiotic gene conversion rates from population genetic data.

Gene conversion plays an important part in shaping genetic diversity in populations, yet estimating the rate at which it occurs is difficult because of the short lengths of DNA involved. We have developed a new statistical approach to estimating gene conversion rates from genetic variation, by exten...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Gay, J, Myers, S, McVean, G
Format:	Journal article
Sprog:	English
Udgivet:	2007

Lignende værker

Estimating recombination rates from population-genetic data.
af: Stumpf, M, et al.
Udgivet: (2003)

Estimating recombination rates from genetic variation in humans.
af: Auton, A, et al.
Udgivet: (2012)

The distribution and causes of meiotic recombination in the human genome.
af: Myers, S, et al.
Udgivet: (2006)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination.
af: Myers, S, et al.
Udgivet: (2010)

Estimating Selection Coefficients in Spatially Structured Populations from Time Series Data of Allele Frequencies
af: Mathieson, I, et al.
Udgivet: (2013)

Estimating selection coefficients in spatially structured populations from time series data of allele frequencies.
af: Mathieson, I, et al.
Udgivet: (2013)

Recombination rate estimation in the presence of hotspots.
af: Auton, A, et al.
Udgivet: (2007)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination
af: Myers, Simon, et al.
Udgivet: (2010)

Recombination Rates, their local variation and the estimated number of hotspots in the human genome.
af: Stumpf, M, et al.
Udgivet: (2003)

A coalescent-based method for detecting and estimating recombination from gene sequences.
af: McVean, G, et al.
Udgivet: (2002)

Evolutionary genetics: what is driving male mutation?
af: McVean, G
Udgivet: (2000)

PRDM9 marks the spot.
af: McVean, G, et al.
Udgivet: (2010)

Dating genomic variants and shared ancestry in population-scale sequencing data.
af: Patrick K Albers, et al.
Udgivet: (2020-01-01)

A model-based approach to capture genetic variation for future association studies.
af: Eyheramendy, S, et al.
Udgivet: (2007)

Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters.
af: Choi, K, et al.
Udgivet: (2013)

Estimating diversifying selection and functional constraint in the presence of recombination.
af: Wilson, D, et al.
Udgivet: (2006)

Perspectives on human genetic variation from the HapMap Project.
af: McVean, G, et al.
Udgivet: (2005)

Perspectives on human genetic variation from the HapMap project
af: McVean, G, et al.
Udgivet: (2005)

A fine-scale map of recombination rates and hotspots across the human genome.
af: Myers, S, et al.
Udgivet: (2005)

A structured ancestral population for the evolution of modern humans.
af: Harding, R, et al.
Udgivet: (2004)

Differential confounding of rare and common variants in spatially structured populations
af: Mathieson, I, et al.
Udgivet: (2012)

Differential confounding of rare and common variants in spatially structured populations.
af: Mathieson, I, et al.
Udgivet: (2012)

A statistical method for predicting classical HLA alleles from SNP data.
af: Leslie, S, et al.
Udgivet: (2008)

The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana
af: Erik Wijnker, et al.
Udgivet: (2013-12-01)

The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis.
af: Jolley, K, et al.
Udgivet: (2005)

Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data.
af: Zhu, S, et al.
Udgivet: (2017)

The estimation of recombination rates from population genetic data
af: Auton, A
Udgivet: (2007)

The structure of linkage disequilibrium around a selective sweep.
af: McVean, G
Udgivet: (2007)

Estimating recombination rates from population genetic data.
af: Fearnhead, P, et al.
Udgivet: (2001)

What drives recombination hotspots to repeat DNA in humans?
af: McVean, G
Udgivet: (2010)

A genealogical interpretation of principal components analysis.
af: McVean, G
Udgivet: (2009)

Linkage Disequilibrium, Recombination and Selection
af: McVean, G
Udgivet: (2008)

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.
af: Cortes, A, et al.
Udgivet: (2019)

The impact of age on genetic risk for common diseases
af: Jiang, X, et al.
Udgivet: (2021)

The impact of age on genetic risk for common diseases.
af: Xilin Jiang, et al.
Udgivet: (2021-08-01)

Interrogating genetic variation in the HLA using high throughput technologies
af: McVean, G, et al.
Udgivet: (2012)

Characterization of meiotic crossovers and gene conversion by whole-genome sequencing in <it>Saccharomyces cerevisiae</it>
af: Wijeratne Asela J, et al.
Udgivet: (2009-10-01)

THE LIMITATIONS OF VARIANT CALLING ALGORITHMS FOR CLASSICAL HLA GENES FROM WHOLE GENOME SEQUENCE DATA
af: Cox, C, et al.
Udgivet: (2012)

Neuroinflammation - using big data to inform clinical practice.
af: Dendrou, C, et al.
Udgivet: (2016)

Reply to: "FaST-LMM-Select for addressing confounding from spatial structure and rare variants".
af: Mathieson, I, et al.
Udgivet: (2013)