303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.

Chi tiết về thư mục
Những tác giả chính:	Chuaiphichai, S, Mcneill, E, Douglas, G, Crabtree, M, Bendall, J, Hale, A, Alp, N, Channon, K
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2014

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Bằng: Chuaiphichai, S, et al.
Được phát hành: (2014)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
Bằng: Chuaiphichai, S, et al.
Được phát hành: (2014)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
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GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
Bằng: Tatham, A, et al.
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Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
Bằng: Carnicer, R, et al.
Được phát hành: (2012)

Endothelial-targeted GTP cyclohydrolase I overexpression increases endothelial tetrahydrobiopterin levels and preserves eNOS coupling in eNOS overexpressing mice
Bằng: Bendall, J, et al.
Được phát hành: (2004)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
Bằng: Alp, N, et al.
Được phát hành: (2003)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
Bằng: Alp, N, et al.
Được phát hành: (2003)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
Bằng: Alp, N, et al.
Được phát hành: (2003)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
Bằng: Alp, N, et al.
Được phát hành: (2003)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
Bằng: Alp, N, et al.
Được phát hành: (2004)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
Bằng: Du, Y, et al.
Được phát hành: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
Bằng: Du, Y, et al.
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Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.
Bằng: Antoniades, C, et al.
Được phát hành: (2011)

Induction of vascular GTP-cyclohydrolase i and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis
Bằng: Antoniades, C, et al.
Được phát hành: (2011)

Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
Bằng: Chen, A, et al.
Được phát hành: (2005)

A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in vascular resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice
Bằng: Chuaiphichai, S, et al.
Được phát hành: (2017)

Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
Bằng: Crabtree, M, et al.
Được phát hành: (2012)

Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
Bằng: Chen, A, et al.
Được phát hành: (2006)

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
Bằng: Bendall, J, et al.
Được phát hành: (2005)

Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
Bằng: Alp, N, et al.
Được phát hành: (2002)

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
Bằng: Vanessa A. N. Kraft, et al.
Được phát hành: (2019-12-01)

GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
Bằng: Khoo, J, et al.
Được phát hành: (2004)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
Bằng: Adlam, D, et al.
Được phát hành: (2012)

Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
Bằng: Crabtree, M, et al.
Được phát hành: (2009)

Conditional knockout of GCH1 in leukocytes and endothelial cells: A novel model to study tetrahydrobiopterin-dependent NOS functions in vivo
Bằng: McNeill, E, et al.
Được phát hành: (2012)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
Bằng: Adlam, D, et al.
Được phát hành: (2012)

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
Bằng: Cai, S, et al.
Được phát hành: (2002)

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
Bằng: Ryan, B, et al.
Được phát hành: (2014)

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
Bằng: Cai, S, et al.
Được phát hành: (2004)

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
Bằng: Adlam, D, et al.
Được phát hành: (2007)

Rapid Effects of Atorvastatin on Tetrahydrobiopterin-Mediated eNOS Coupling in Human Arteries, is Mediated by Stimulation of Vascular GTP-Cyclohydrolase
Bằng: Antoniades, C, et al.
Được phát hành: (2011)

cGMP Inhibits GTP Cyclohydrolase I Activity and Biosynthesis of Tetrahydrobiopterin in Human Umbilical Vein Endothelial Cells
Bằng: Hiroaki Shiraishi, et al.
Được phát hành: (2003-01-01)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
Bằng: Carnicer, R, et al.
Được phát hành: (2011)

Statin Increases GTP Cyclohydrolase I mRNA and 5,6,7,8-Tetrahydrobiopterin in Vascular Endothelial Cells
Bằng: Hattori Yoshiyuki, et al.
Được phát hành: (2006-08-01)

Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
Bằng: Du, Y, et al.
Được phát hành: (2008)

Deficiency in endothelial cell tetrahydrobiopterin increases resistance vascular remodelling, blood pressure, and susceptibility to aortic abdominal aneurysm in response to angiotensin II
Bằng: Chuaiphichai, S, et al.
Được phát hành: (2018)

GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats.
Bằng: Meininger, C, et al.
Được phát hành: (2004)

303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.

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