Understanding the role of the TOPBP1 and BLM interaction in promoting genome stability

<p>The ability to sense, respond to and repair DNA damage is essential in normal development and survival of an organism. A number of human congenital syndromes are associated with mutations in pathways involved in the DNA damage response, including Seckel and Bloom syndromes. Such diseases...

Description complète

Détails bibliographiques
Auteur principal: Smethurst, E
Autres auteurs: Niedzwiedz, W
Format: Thèse
Publié: 2017