Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis.
Two main pieces of neurobiological evidence are adduced to support an early neurodevelopmental component to schizophrenia. Firstly, an abnormal distribution of neurons, especially interstitial white matter neurons (IWMNs). Secondly, decreased expression of reelin, a key developmental signalling mole...
Main Authors: | Eastwood, S, Harrison, P |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2003
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פריטים דומים
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Altered density of interstitial white matter and layer I neurons is accompanied by decreased reelin expression in the dorsolateral prefrontal cortex in schizophrenia
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Interstitial white matter neuron density in the dorsolateral prefrontal cortex and parahippocampal gyrus in schizophrenia.
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Cellular basis of reduced cortical reelin expression in schizophrenia.
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Reelin mRNA is decreased in neurons of the hippocampus and temporal cortex in schizophrenia: A cellular in situ hybridisation study
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Analysis of Reelin in autism.
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