Retinal repair by transplantation of photoreceptor precursors.

Retinal repair by transplantation of photoreceptor precursors.

Photoreceptor loss causes irreversible blindness in many retinal diseases. Repair of such damage by cell transplantation is one of the most feasible types of central nervous system repair; photoreceptor degeneration initially leaves the inner retinal circuitry intact and new photoreceptors need only...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Maclaren, R, Pearson, R, MacNeil, A, Douglas, R, Salt, T, Akimoto, M, Swaroop, A, Sowden, J, Ali, R
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2006

Antzeko izenburuak

Immature neural retinal cells integrate and differentiate into photoreceptors when transplanted into the mouse subreitnal space at post-natal day 1
nork: Maclaren, R, et al.
Argitaratua: (2005)

Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.
nork: West, E, et al.
Argitaratua: (2008)

Cell transplantation strategies for retinal repair.
nork: West, E, et al.
Argitaratua: (2009)

Overexpression of developmentally regulated neurotrophins in the adult mouse retina to facilitate integration of transplanted photoreceptor precursor cells
nork: West, E, et al.
Argitaratua: (2008)

Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival.
nork: West, E, et al.
Argitaratua: (2012)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
nork: Singh, M, et al.
Argitaratua: (2016)

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
nork: R. A. Pearson, et al.
Argitaratua: (2016-10-01)

Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
nork: Pearson, R, et al.
Argitaratua: (2010)

Manipulation of the Recipient Retinal Environment by Ectopic Expression of Neurotrophic Growth Factors Can Improve Transplanted Photoreceptor Integration and Survival
nork: E. L. West, et al.
Argitaratua: (2012-05-01)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
nork: Mandeep S. Singh, et al.
Argitaratua: (2016-11-01)

Cone fusion confusion in photoreceptor transplantation
nork: MacLaren, R
Argitaratua: (2017)

Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina
nork: R. A. Pearson, et al.
Argitaratua: (2010-04-01)

Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.
nork: West, E, et al.
Argitaratua: (2010)

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.
nork: Singh, MS, et al.
Argitaratua: (2013)

Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye.
nork: MacNeil, A, et al.
Argitaratua: (2007)

Outer segment formation of transplanted photoreceptor precursor cells.
nork: Dominic Eberle, et al.
Argitaratua: (2012-01-01)

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.
nork: Budd A Tucker, et al.
Argitaratua: (2011-04-01)

Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice.
nork: Budd A Tucker, et al.
Argitaratua: (2015-01-01)

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
nork: Anai Gonzalez-Cordero, et al.
Argitaratua: (2017-09-01)

CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids
nork: Deng Pan, et al.
Argitaratua: (2023-12-01)

Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa
nork: Orlans, HO, et al.
Argitaratua: (2019)

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells
nork: Saeed Khalili, et al.
Argitaratua: (2018-12-01)

Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina.
nork: Kokkinopoulos, I, et al.
Argitaratua: (2008)

Induced pluripotent stem cells and derivative photoreceptor precursors as therapeutic cells for retinal degenerations
nork: Rupendra Shrestha, et al.
Argitaratua: (2020-01-01)

Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.
nork: Aslam, SA, et al.
Argitaratua: (2013)

Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia.
nork: Tolmachova, T, et al.
Argitaratua: (2010)

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa
nork: Budd A Tucker, et al.
Argitaratua: (2013-08-01)

Metabolic rescue of cone photoreceptors in retinitis pigmentosa
nork: Henry J Kaplan, et al.
Argitaratua: (2021-01-01)

Retinal Thickening and Photoreceptor Loss in HIV Eyes without Retinitis.
nork: Cheryl A Arcinue, et al.
Argitaratua: (2015-01-01)

cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates
nork: Swathi Lingam, et al.
Argitaratua: (2021-08-01)

AAV-Mediated Expression of Secreted Human Ciliary Neurotropic Factor (hCNTF) Leads to Long-Term Preservation of Cone Photoreceptors in an Autosomal Recessive Model of Retinitis Pigmentosa
nork: Lipinski, D, et al.
Argitaratua: (2013)

Inner retinal thickening affects microperimetry thresholds in the presence of photoreceptor thinning in patients with RPGR retinitis pigmentosa
nork: Jolly, JK, et al.
Argitaratua: (2020)

Accelerated Development of Rod Photoreceptors in Retinal Organoids Derived from Human Pluripotent Stem Cells by Supplementation with 9-cis Retinal
nork: Ryan A. Kelley, et al.
Argitaratua: (2020-06-01)

In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.
nork: Buch, P, et al.
Argitaratua: (2006)

Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases.
nork: Sunil K Parapuram, et al.
Argitaratua: (2010-11-01)

Photoreceptor Differentiation following Transplantation of Allogeneic Retinal Progenitor Cells to the Dystrophic Rhodopsin Pro347Leu Transgenic Pig
nork: H. Klassen, et al.
Argitaratua: (2012-01-01)

Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
nork: Holly Y Chen, et al.
Argitaratua: (2023-03-01)

Neuroprotection of cone photoreceptors in retinitis pigmentosa
nork: Lipinski, D, et al.
Argitaratua: (2013)

Multiphoton response of retinal rod photoreceptors
nork: Vasilios Alexiades, et al.
Argitaratua: (2007-02-01)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
nork: Sang Joon Lee, et al.
Argitaratua: (2025-01-01)