Cell fate mechanisms in colorectal cancer

Cell fate mechanisms in colorectal cancer

<p>Colorectal cancer (CRC) arises in part from the dysregulation of cellular proliferation, associated with the canonical Wnt pathway, and differentiation, effected by the Notch signalling network. In this thesis, we develop a mathematical model of ordinary differential equations (ODEs) for th...

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Bibliografiske detaljer
Hovedforfatter:	Kay, SK
Andre forfattere:	Gavaghan, D
Format:	Thesis
Sprog:	English
Udgivet:	2014
Fag:	Biology and other natural sciences (mathematics) Ordinary differential equations Biology Mathematics Computational biochemistry Gastroenterology Mathematical biology Physiology and anatomy Computer science (mathematics)

Lignende værker

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Mathematical models of the retina in health and disease
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Large-scale layered systems and synthetic biology: model reduction and decomposition
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Application of software engineering methodologies to the development of mathematical biological models
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Mathematical approaches to modelling healing of full thickness circular skin wounds
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Spatiotemporal behaviour of stochastic and continuum models for biological signalling on stationary and growing domains
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Comparing stochastic discrete and deterministic continuum models of cell migration
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An integrative framework for computational modelling of cardiac electromechanics in the mouse
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A multi-scale computational investigation of cardiac electrophysiology and arrhythmias in acute ischaemia
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Towards a computational model of the colonic crypt with a realistic, deformable geometry
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Mathematical modelling of flow and transport phenomena in tissue engineering
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A fictitious domain approach for hybrid simulations of eukaryotic chemotaxis
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Mathematical modelling of Centrosomin incorporation in Drosophila centrosomes
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Vasculature reconstruction from 3D cryomicrotome images
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On two-phase flow models for cell motility
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Modelling divisive inhibition in the primary visual cortex from optogenetic circuit mapping data
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Multi-scale modelling of blood flow in the coronary microcirculation
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Malaria elimination modelling in the context of antimalarial drug resistance
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Finite element simulation of a poroelastic model of the CSF system in the human brain during an infusion test
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Mathematical modelling of metabolism and acidity in cancer
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Modelling and comparing protein interaction networks using subgraph counts
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Genomic imprinting and sex allocation
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Udgivet: (2009)

A sex allocation theory for vertebrates: combining local resource competition and condition-dependent allocation
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Udgivet: (2007)

Parameter recovery in AC solution-phase voltammetry and a consideration of some issues arising when applied to surface-confined reactions
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Udgivet: (2014)

Probabilistic bias in genotype-phenotype maps
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Automatic simplification of differential equation models by a posteriori analysis
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The buckling of capillaries in tumours
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Udgivet: (2011)

Ligand binding and signalling by the T cell antigen receptor and CD28
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Udgivet: (2014)

Impact of tissue microstructure on a model of cardiac electromechanics based on MRI data
af: Carapella, V
Udgivet: (2013)

Effective design of marine reserves: incorporating alongshore currents, size structure, and uncertainty
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Mathematical evolutionary epidemiology: limited epitopes, evolution of strain structures and age-specificity
af: Cherif, A
Udgivet: (2015)

Modelling of calcium handling in genetically modified mice
af: Li, L
Udgivet: (2011)

Evolvability: a formal approach
af: Gallagher, A
Udgivet: (2009)

Mathematical models of cranial neural crest cell migration
af: Dyson, L
Udgivet: (2013)

Stochastic modelling and simulation in cell biology
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The evolution of cooperation, especially in humans
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Udgivet: (2011)

Cardiac mechanical model personalisation and its clinical applications
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Biomimetic and autonomic server ensemble orchestration
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Recent modelling frameworks for systems of interacting particles
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In silico modelling of tumour-induced angiogenesis
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