Ruthenium half-sandwich complexes bound to protein kinase Pim-1.
(Figure Presented) Keeping in shape with half a sandwich: The structure of a picomolar organoruthenium inhibitor bound to the ATP-binding site of the protein kinase Pim-1 (see picture) demonstrates that the ruthenium center has solely a structural role in organizing the organic ligands in the three-...
Prif Awduron: | Debreczeni, J, Bullock, A, Atilla, G, Williams, D, Bregman, H, Knapp, S, Meggers, E |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2006
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Eitemau Tebyg
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Ruthenium half-sandwich complexes bound to protein kinase Pim-1
gan: Debreczeni, J, et al.
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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
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Structure and substrate specificity of the Pim-1 kinase
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Cyhoeddwyd: (2005) -
Structure and substrate specificity of the Pim-1 kinase.
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Cyhoeddwyd: (2005)