Ruthenium half-sandwich complexes bound to protein kinase Pim-1.
(Figure Presented) Keeping in shape with half a sandwich: The structure of a picomolar organoruthenium inhibitor bound to the ATP-binding site of the protein kinase Pim-1 (see picture) demonstrates that the ruthenium center has solely a structural role in organizing the organic ligands in the three-...
Príomhchruthaitheoirí: | Debreczeni, J, Bullock, A, Atilla, G, Williams, D, Bregman, H, Knapp, S, Meggers, E |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2006
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Míreanna comhchosúla
Míreanna comhchosúla
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Ruthenium half-sandwich complexes bound to protein kinase Pim-1
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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
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Structure and substrate specificity of the Pim-1 kinase
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Structure and substrate specificity of the Pim-1 kinase.
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