Expression of the thermogenic nuclear hormone receptor coactivator PGC-1alpha is reduced in the adipose tissue of morbidly obese subjects.
Peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) is an accessory protein which can potentiate the transcriptional activation function of many nuclear hormone receptors. Its tissue distribution and physiological studies suggest that its principal in vivo roles are to pr...
Main Authors: | Semple, R, Crowley, VC, Sewter, C, Laudes, M, Christodoulides, C, Considine, R, Vidal-Puig, A, O'Rahilly, S |
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Format: | Journal article |
Language: | English |
Published: |
2004
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