Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis.

Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis.

Melioidosis is a severe infection caused by the flagellated bacterium Burkholderia pseudomallei. The nonsense polymorphism TLR51174C>T is associated with improved outcome in Thais with melioidosis. We hypothesized that other TLR5 variants may modulate the host response and determine outcome i...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Chantratita, N, Tandhavanant, S, Myers, N, Chierakul, W, Robertson, J, Mahavanakul, W, Singhasivanon, P, Emond, M, Peacock, S, West, T
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Nature Publishing Group 2014

समान संसाधन

Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand
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Impaired TLR5 functionality is associated with survival in melioidosis.
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Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis
द्वारा: Wright, S, और अन्य
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Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis.
द्वारा: West, T, और अन्य
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The role of NOD2 in murine and human melioidosis.
द्वारा: Myers, N, और अन्य
प्रकाशित: (2014)

Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide
द्वारा: Chantratita, N, और अन्य
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Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.
द्वारा: Chantratita, N, और अन्य
प्रकाशित: (2013)

Melioidosis in 6 tsunami survivors in southern Thailand.
द्वारा: Chierakul, W, और अन्य
प्रकाशित: (2005)

Blood transcriptomics to characterize key biological pathways and identify biomarkers for predicting mortality in melioidosis
द्वारा: Yimthin, T, और अन्य
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A Nonsense Mutation in TLR5 Is Associated with Survival and Reduced IL-10 and TNF-α Levels in Human Melioidosis
द्वारा: Chaichana, P, और अन्य
प्रकाशित: (2017)

Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis.
द्वारा: Chantratita, N, और अन्य
प्रकाशित: (2007)

Recurrent melioidosis in patients in northeast Thailand is frequently due to reinfection rather than relapse.
द्वारा: Maharjan, B, और अन्य
प्रकाशित: (2005)

Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.
द्वारा: Koh, G, और अन्य
प्रकाशित: (2011)

Rheumatological manifestations in patients with melioidosis.
द्वारा: Teparrakkul, P, और अन्य
प्रकाशित: (2008)

Short report: Melioidosis in Myanmar: forgotten but not gone?
द्वारा: Wuthiekanun, V, और अन्य
प्रकाशित: (2006)

Intensity of exposure and incidence of melioidosis in Thai children.
द्वारा: Cheng, A, और अन्य
प्रकाशित: (2008)

Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in Northeast Thailand
द्वारा: Seng, R, और अन्य
प्रकाशित: (2024)

Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in northeast Thailand
द्वारा: Seng, R, और अन्य
प्रकाशित: (2023)

Risk factors for recurrent melioidosis in northeast Thailand.
द्वारा: Limmathurotsakul, D, और अन्य
प्रकाशित: (2006)

Prospective clinical evaluation of the accuracy of 16S rRNA real-time PCR assay for the diagnosis of melioidosis.
द्वारा: Chantratita, N, और अन्य
प्रकाशित: (2007)

The role and significance of sputum cultures in the diagnosis of melioidosis.
द्वारा: Huis in 't Veld, D, और अन्य
प्रकाशित: (2005)

Dosing regimens of cotrimoxazole (trimethoprim-sulfamethoxazole) for melioidosis.
द्वारा: Cheng, A, और अन्य
प्रकाशित: (2009)

Role and significance of quantitative urine cultures in diagnosis of melioidosis.
द्वारा: Limmathurotsakul, D, और अन्य
प्रकाशित: (2005)

Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis.
द्वारा: Cheng, A, और अन्य
प्रकाशित: (2008)

Diabetes mellitus, insulin, and melioidosis in Thailand.
द्वारा: Simpson, A, और अन्य
प्रकाशित: (2003)

Short report: disease severity and outcome of melioidosis in HIV coinfected individuals.
द्वारा: Chierakul, W, और अन्य
प्रकाशित: (2005)

Rapid immunofluorescence microscopy for diagnosis of melioidosis.
द्वारा: Wuthiekanun, V, और अन्य
प्रकाशित: (2005)

Addition of trimethoprim-sulfamethoxazole to ceftazidime during parenteral treatment of melioidosis is not associated with a long-term outcome benefit
द्वारा: Chierakul, W, और अन्य
प्रकाशित: (2007)

Short report: The role and significance of sputum cultures in the diagnosis of melioidosis
द्वारा: T'Veld, D, और अन्य
प्रकाशित: (2005)

Melioidosis
द्वारा: Wiersinga, W, और अन्य
प्रकाशित: (2018)

Development of antibodies to Burkholderia pseudomallei during childhood in melioidosis-endemic northeast Thailand.
द्वारा: Wuthiekanun, V, और अन्य
प्रकाशित: (2006)

Short report: Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis
द्वारा: Cheng, A, और अन्य
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Pharmacokinetic and pharmacodynamic assessment of co-amoxiclav in the treatment of melioidosis.
द्वारा: Chierakul, W, और अन्य
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Patterns of organ involvement in recurrent melioidosis.
द्वारा: Limmathurotsakul, D, और अन्य
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Innate sensing of bacterial flagellin in acute and chronic intestinal inflammation
द्वारा: Nordlander, S
प्रकाशित: (2013)

Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast
द्वारा: Buscaill, P, और अन्य
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Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides
द्वारा: Buscaill, P, और अन्य
प्रकाशित: (2019)

Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei.
द्वारा: Wiersinga, W, और अन्य
प्रकाशित: (2006)

Role of Burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis.
द्वारा: Limmathurotsakul, D, और अन्य
प्रकाशित: (2014)

A simple scoring system to differentiate between relapse and re-infection in patients with recurrent melioidosis
द्वारा: Limmathurotsakul, D, और अन्य
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