The β2-adrenergic receptor is a molecular switch for neuroendocrine transdifferentiation of prostate cancer cells

The β2-adrenergic receptor is a molecular switch for neuroendocrine transdifferentiation of prostate cancer cells

The incidence of treatment-related neuroendocrine (NE) prostate cancer (t-NEPC) is rising as more potent drugs targeting the androgen signaling axis are clinically implemented. Neuroendocrine transdifferentiation (NEtD), an putative initial step in t-NEPC development, is induced by androgen deprivat...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Braadland, PR, Ramberg, H, Grytli, HH, Urbanucci, A, Nielsen, HK, Guldvik, IJ, Engedal, A, Ketola, K, Wang, W, Svindland, A, Mills, IG, Bjartell, A, Tasken, KA
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	American Association of Cancer Research 2019

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β-Adrenergic receptor signaling in prostate cancer
nork: Peder Rustøen Braadland, et al.
Argitaratua: (2015-01-01)

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nork: Guldvik, IJ, et al.
Argitaratua: (2022)

Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
nork: Guldvik, IJ, et al.
Argitaratua: (2024)

Identification and validation of leucine-rich α-2-glycoprotein 1 as a noninvasive biomarker for improved precision in prostate cancer risk stratification
nork: Guldvik, IJ, et al.
Argitaratua: (2020)

Non-selective beta-blocker use is associated with reduced cancer recurrence after radical prostatectomy: A prospective cohort study on 11256 radically operated patients
nork: S. Sivanesan, et al.
Argitaratua: (2020-07-01)

Regulation of PBX3 expression by androgen and Let-7d in prostate cancer
nork: Berge Viktor, et al.
Argitaratua: (2011-05-01)

Therapeutic Exploitation of Neuroendocrine Transdifferentiation Drivers in Prostate Cancer
nork: Zoe R. Maylin, et al.
Argitaratua: (2024-12-01)

Neuroendocrine transdifferentiation in human cancer: molecular mechanisms and therapeutic targets
nork: Jun Jiang, et al.
Argitaratua: (2024-10-01)

Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
nork: Lina Merkens, et al.
Argitaratua: (2022-02-01)

Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells.
nork: Ilaria Guerriero, et al.
Argitaratua: (2021-01-01)

Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
nork: Ingrid J. Guldvik, et al.
Argitaratua: (2020-10-01)

Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer
nork: Baijun Dong, et al.
Argitaratua: (2020-12-01)

Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer
nork: Ingrid Jenny Guldvik, et al.
Argitaratua: (2022-11-01)

Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model
nork: Vincent Faugeroux, et al.
Argitaratua: (2020-04-01)

Mechanisms of cancer transdifferentiation
nork: Lee, Jane Jia Hui
Argitaratua: (2022)

Attractor of a nonlinear hybrid reaction–diffusion model of neuroendocrine transdifferentiation of human prostate cancer cells with time-lags
nork: Kaihong Zhao
Argitaratua: (2023-04-01)

Cross Modulation between the Androgen Receptor Axis and Protocadherin-PC in Mediating Neuroendocrine Transdifferentiation and Therapeutic Resistance of Prostate Cancer
nork: Stéphane Terry, et al.
Argitaratua: (2013-07-01)

The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells.
nork: Jaroslaw Thomas Dankert, et al.
Argitaratua: (2018-01-01)

177LU-PSMA AND 177LU-DOTATATE AS THERAPY ALTERNATIVES FOR METACHRONOUS TRANSDIFFERENTIATED PROSTATE AND NEUROENDOCRINE TUMORS - CASE REPORT
nork: Beatriz Birelli do Nascimento, et al.
Argitaratua: (2024-04-01)

Transdifferentiation of extraembryonic endoderm in mouse
nork: Ninomiya, Y, et al.
Argitaratua: (2005)

Bromodomain-containing proteins in prostate cancer.
nork: Urbanucci, A, et al.
Argitaratua: (2017)

Transdifferentiation of fibroblasts to neural stem cells
nork: Cassady, John P
Argitaratua: (2014)

Monocytes Do Not Transdifferentiate into Proper Osteoblasts
nork: Andreas Schmitt, et al.
Argitaratua: (2012-01-01)

Role of angiogenic transdifferentiation in vascular recovery
nork: John P. Cooke, et al.
Argitaratua: (2023-05-01)

Hypothesis about Transdifferentiation As Backbone of Malignancy
nork: Jean Piechowski
Argitaratua: (2017-06-01)

Bayesian Networks Predict Neuronal Transdifferentiation
nork: Richard I. Ainsworth, et al.
Argitaratua: (2018-07-01)

Reprogramming, oscillations and transdifferentiation in epigenetic landscapes
nork: Bivash Kaity, et al.
Argitaratua: (2018-05-01)

Transdifferentiation-inducing <it>HCCR-1 </it>oncogene
nork: Kim Jin, et al.
Argitaratua: (2010-06-01)

The role of DNA demethylation in liver to pancreas transdifferentiation
nork: Adi Har-Zahav, et al.
Argitaratua: (2022-09-01)

Retinoic Acid-Induced Epidermal Transdifferentiation in Skin
nork: Yoshihiro Akimoto, et al.
Argitaratua: (2014-06-01)

Exploring the mechanisms of differentiation, dedifferentiation, reprogramming and transdifferentiation.
nork: Li Xu, et al.
Argitaratua: (2014-01-01)

Transdifferentiation of cancer stem cells into endothelial cells
nork: Porta Caterina
Argitaratua: (2011-10-01)

Exogenous Oct-4 inhibits lens transdifferentiation in the newt Notophthalmus viridescens.
nork: Rital B Bhavsar, et al.
Argitaratua: (2014-01-01)

Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
nork: Emanuele Pignatti, et al.
Argitaratua: (2020-04-01)

Experimental analysis of the transdifferentiation of visceral to parietal endoderm in the mouse.
nork: Ninomiya, Y, et al.
Argitaratua: (2005)

Adipo-Epithelial Transdifferentiation in In Vitro Models of the Mammary Gland
nork: Jessica Perugini, et al.
Argitaratua: (2024-05-01)

B lymphocytes transdifferentiate into immunosuppressive erythroblast-like cells
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Targeting β-cell dedifferentiation and transdifferentiation: opportunities and challenges
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Argitaratua: (2021-08-01)

Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models
nork: Dai Shuzhen, et al.
Argitaratua: (2009-09-01)

Adrenergic regulation of adipocyte metabolism.
nork: J N Fain, et al.
Argitaratua: (1983-08-01)