Palladium catalysed elaboration of codeine and morphine
Palladium catalysed coupling reactions of 6-O-tert-butyldimethylsilyl-1-bromocodeine and 6-O-tert-butyldimethylsilyl-3-trifluoromethylsulfonylmorphine allow a range of substituted analogues of codeine in the 1-position and morphine in the 3-position to be efficiently and selectively prepared.
المؤلفون الرئيسيون: | , , , |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2001
|