The effects of spiradoline (U-62066E), a kappa-opioid receptor agonist, on neuroendocrine function in man.
1. Opioid drugs act on specific receptors which are principally classified into mu, delta and kappa subtypes. Spiradoline (U-62066E) is a kappa-selective agent which has been shown to possess potent anti-nociceptive effects but does not show cross tolerance with morphine. 2. We have assessed the neu...
Auteurs principaux: | Ur, E, Wright, D, Bouloux, P, Grossman, A |
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Format: | Journal article |
Langue: | English |
Publié: |
1997
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