Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure.
The combination therapy of the Artemisinin-derivative Artemether (ART) with Lumefantrine (LM) (Coartem(R)) is an important malaria treatment regimen in many endemic countries. Resistance to Artemisinin has already been reported, and it is feared that LM resistance (LMR) could also evolve quickly. Th...
| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Public Library of Science
2012
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