A cascade strategy enables a total synthesis of (±)-morphine
Morphine has been a target for synthetic chemists since Robinson proposed its correct structure in 1925, resulting in a large number of total syntheses of morphine alkaloids. Here we report a total synthesis of (±)-morphine that employs two key strategic cyclizations: (i) a diastereoselective...
Main Authors: | Smith, M, Chu, S, Balan, T, Münster, N |
---|---|
Format: | Journal article |
Published: |
Wiley
2016
|
Similar Items
-
A cascade strategy enables a total synthesis of (-)-gephyrotoxin.
by: Chu, S, et al.
Published: (2014) -
Total syntheses of (–)-gephyrotoxin and (±)-morphine
by: Chu, S
Published: (2017) -
ORGN 549-Cascade approaches to the total synthesis of the lepadin alkaloids
by: Thompson, S, et al.
Published: (2008) -
Total synthesis: an enabling science
by: Bastien Nay
Published: (2023-04-01) -
Intrathecal Morphine versus Morphine-Dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement: A Randomized Controlled Trial
by: Omara AF, et al.
Published: (2023-08-01)