A cascade strategy enables a total synthesis of (±)-morphine
Morphine has been a target for synthetic chemists since Robinson proposed its correct structure in 1925, resulting in a large number of total syntheses of morphine alkaloids. Here we report a total synthesis of (±)-morphine that employs two key strategic cyclizations: (i) a diastereoselective...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Izdano: |
Wiley
2016
|