Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells.
The pressing need for broad-spectrum antivirals could be met by targeting host rather than viral processes. Cholesterol biosynthesis within the infected cell is one promising target for a large number of viral systems, including hepatitis C virus (HCV), hepatitis B virus (HBV) and HIV. Liposomes dev...
Autores principales: | Pollock, S, Nichita, N, Böhmer, A, Radulescu, C, Dwek, R, Zitzmann, N |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2010
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