Towards the first antibody-free serum biomarker assay for NAFLD
Liver biopsy is the reference standard for NAFLD diagnosis and staging. NAFLD can be assessed less invasively using immunoassays to detect serum biomarkers. However, biomarkers can degrade due to sample storage conditions and therefore may not be detected using these antibody-based assays. Detection...
| Main Authors: | , , , , , |
|---|---|
| Format: | Conference item |
| Published: |
OMICS International
2017
|
| _version_ | 1826304526947188736 |
|---|---|
| author | Gangadharan, B Kumar, A Cobbold, J Thursz, M Dwek, RA Zitzmann, N |
| author_facet | Gangadharan, B Kumar, A Cobbold, J Thursz, M Dwek, RA Zitzmann, N |
| author_sort | Gangadharan, B |
| collection | OXFORD |
| description | Liver biopsy is the reference standard for NAFLD diagnosis and staging. NAFLD can be assessed less invasively using immunoassays to detect serum biomarkers. However, biomarkers can degrade due to sample storage conditions and therefore may not be detected using these antibody-based assays. Detection of biomarkers by mass spectrometry (MS) overcomes this disadvantage. |
| first_indexed | 2024-03-07T06:19:10Z |
| format | Conference item |
| id | oxford-uuid:f222e887-0047-417f-ae4d-623769e15a92 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T06:19:10Z |
| publishDate | 2017 |
| publisher | OMICS International |
| record_format | dspace |
| spelling | oxford-uuid:f222e887-0047-417f-ae4d-623769e15a922022-03-27T12:01:14ZTowards the first antibody-free serum biomarker assay for NAFLDConference itemhttp://purl.org/coar/resource_type/c_5794uuid:f222e887-0047-417f-ae4d-623769e15a92Symplectic Elements at OxfordOMICS International2017Gangadharan, BKumar, ACobbold, JThursz, MDwek, RAZitzmann, NLiver biopsy is the reference standard for NAFLD diagnosis and staging. NAFLD can be assessed less invasively using immunoassays to detect serum biomarkers. However, biomarkers can degrade due to sample storage conditions and therefore may not be detected using these antibody-based assays. Detection of biomarkers by mass spectrometry (MS) overcomes this disadvantage. |
| spellingShingle | Gangadharan, B Kumar, A Cobbold, J Thursz, M Dwek, RA Zitzmann, N Towards the first antibody-free serum biomarker assay for NAFLD |
| title | Towards the first antibody-free serum biomarker assay for NAFLD |
| title_full | Towards the first antibody-free serum biomarker assay for NAFLD |
| title_fullStr | Towards the first antibody-free serum biomarker assay for NAFLD |
| title_full_unstemmed | Towards the first antibody-free serum biomarker assay for NAFLD |
| title_short | Towards the first antibody-free serum biomarker assay for NAFLD |
| title_sort | towards the first antibody free serum biomarker assay for nafld |
| work_keys_str_mv | AT gangadharanb towardsthefirstantibodyfreeserumbiomarkerassayfornafld AT kumara towardsthefirstantibodyfreeserumbiomarkerassayfornafld AT cobboldj towardsthefirstantibodyfreeserumbiomarkerassayfornafld AT thurszm towardsthefirstantibodyfreeserumbiomarkerassayfornafld AT dwekra towardsthefirstantibodyfreeserumbiomarkerassayfornafld AT zitzmannn towardsthefirstantibodyfreeserumbiomarkerassayfornafld |