The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease.

The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease.

A genome-wide association study (GWAS) of bladder cancer identified a genetic marker rs8102137 within the 19q12 region as a novel susceptibility variant. This marker is located upstream of the CCNE1 gene, which encodes cyclin E, a cell-cycle protein. We performed genetic fine-mapping analysis of the...

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Bibliographic Details
Main Authors: Fu, Y, Kohaar, I, Moore, L, Lenz, P, Figueroa, J, Tang, W, Porter-Gill, P, Chatterjee, N, Scott-Johnson, A, Garcia-Closas, M, Muchmore, B, Baris, D, Paquin, A, Ylaya, K, Schwenn, M, Apolo, AB, Karagas, MR, Tarway, M, Johnson, A, Mumy, A, Schned, A, Guedez, L, Jones, M, Kida, M, Hosain, G
Format: Journal article
Language:English
Published: American Association for Cancer Research Inc. 2014

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