FLT3 receptor and ligand are dispensable for maintenance and posttransplantation expansion of mouse hematopoietic stem cells.

FLT3 receptor and ligand are dispensable for maintenance and posttransplantation expansion of mouse hematopoietic stem cells.

Originally cloned from hematopoietic stem cell (HSC) populations and its ligand being extensively used to promote ex vivo HSC expansion, the FMS-like tyrosine kinase 3 (FLT3; also called FLK2) receptor and its ligand (FL) were expected to emerge as an important physiologic regulator of HSC maintenan...

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Detalhes bibliográficos
Principais autores:	Buza-Vidas, N, Cheng, M, Duarte, S, Charoudeh, H, Jacobsen, SE, Sitnicka, E
Formato:	Journal article
Idioma:	English
Publicado em:	2009

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