Influence of correlated antigen presentation on T-cell negative selection in the thymus

Influence of correlated antigen presentation on T-cell negative selection in the thymus

The thymus is the primary organ for the generation of naive T cells, a key component of the immune system. Tolerance of T cells to self is achieved primarily in the thymic medulla, where immature T cells (thymocytes) sample self-peptides presented by medullary thymic epithelial cells (mTECs). A suff...

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Autors principals:	Banerjee, S, Chapman, SJ
Format:	Journal article
Publicat:	Royal Society 2018

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