Parafibromin is a nuclear protein with a functional monopartite nuclear localization signal.
Parafibromin is a nuclear protein with a tumour suppressor role in the development of non-hereditary and hereditary parathyroid carcinomas, and the hyperparathyroidism-jaw tumour (HPT-JT) syndrome, which is associated with renal and uterine tumours. Nuclear localization signal(s), (NLS(s)), of the 6...
Príomhchruthaitheoirí: | Bradley, K, Bowl, MR, Williams, SE, Ahmad, B, Partridge, C, Patmanidi, A, Kennedy, A, Loh, N, Thakker, R |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2007
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Míreanna comhchosúla
Míreanna comhchosúla
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Parafibromin--functional insights.
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Utilisation of a cryptic non-canonical donor splice site of the gene encoding PARAFIBROMIN is associated with familial isolated primary hyperparathyroidism.
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Parafibromin mutations in hereditary hyperparathyroidism syndromes and parathyroid tumours.
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Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice.
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The roles of the tumor suppressor parafibromin in cancer
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Foilsithe / Cruthaithe: (2022-09-01)