Self-maintaining CD103+ cancer-specific T cells are highly energetic with rapid cytotoxic and effector responses

Enrichment of CD103+ tumor-infiltrating T lymphocytes (TIL) is associated with improved outcomes in patients. However, the characteristics of human CD103+ cytotoxic CD8+ T cells (CTL) and their role in tumor control remain unclear. We investigated the features and antitumor mechanisms of CD103+ CTLs...

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Main Authors: Abd Hamid, M, Colin-York, H, Khalid-Alham, N, Browne, M, Cerundolo, L, Chen, J-L, Yao, X, Rosendo-Machado, S, Waugh, C, Maldonado-Perez, D, Bowes, E, Verrill, C, Cerundolo, V, Conlon, CP, Fritzsche, M, Peng, Y, Dong, T
格式: Journal article
語言:English
出版: American Association for Cancer Research 2019