Pause sites promote transcriptional termination of mammalian RNA polymerase II.
Polymerase II (Pol II) transcriptional termination depends on two independent genetic elements: poly(A) signals and downstream terminator sequences. The latter may either promote cotranscriptional RNA cleavage or pause elongating Pol II. We demonstrate that the previously characterized MAZ4 pause el...
| Autori principali: | , , |
|---|---|
| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
2006
|