Development of Erf-mediated craniosynostosis and pharmacological amelioration

Development of Erf-mediated craniosynostosis and pharmacological amelioration

ETS2 repressor factor (<i>ERF</i>) insufficiency causes craniosynostosis (CRS4) in humans and mice. ERF is an ETS domain transcriptional repressor regulated by Erk1/2 phosphorylation via nucleo-cytoplasmic shuttling. Here, we analyze the onset and development of the craniosynostosis phen...

书目详细资料
Main Authors:	Vogiatzi, A, Keklikoglou, K, Makris, K, Richardson, MSW, Fenwick, AL, Robertson, J, Twigg, SRF, Wilkie, AOM
格式:	Journal article
语言:	English
出版:	MDPI 2023

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