Development of Erf-mediated craniosynostosis and pharmacological amelioration

ETS2 repressor factor (<i>ERF</i>) insufficiency causes craniosynostosis (CRS4) in humans and mice. ERF is an ETS domain transcriptional repressor regulated by Erk1/2 phosphorylation via nucleo-cytoplasmic shuttling. Here, we analyze the onset and development of the craniosynostosis phen...

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מידע ביבליוגרפי
Main Authors: Vogiatzi, A, Keklikoglou, K, Makris, K, Richardson, MSW, Fenwick, AL, Robertson, J, Twigg, SRF, Wilkie, AOM
פורמט: Journal article
שפה:English
יצא לאור: MDPI 2023