Development of Erf-mediated craniosynostosis and pharmacological amelioration
ETS2 repressor factor (<i>ERF</i>) insufficiency causes craniosynostosis (CRS4) in humans and mice. ERF is an ETS domain transcriptional repressor regulated by Erk1/2 phosphorylation via nucleo-cytoplasmic shuttling. Here, we analyze the onset and development of the craniosynostosis phen...
| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
MDPI
2023
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