Blockade of OX40-OX40L Interactions Attenuates Allograft Rejection Mediated by CD4 T Cells That Recognize Alloantigen through the Direct but Not Indirect Pathway of Allorecognition

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• A diametric role for OX40 in the response of effector/memory CD4+ T cells and regulatory T cells to alloantigen.
  per: Kinnear, G, et al.
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• Role of OX40-OX40L interactions in the immune response to solid organ allografts
  per: Kinnear, G
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• Anti-OX40 prevents effector T-cell accumulation and CD8+ T-cell mediated skin allograft rejection.
  per: Kinnear, G, et al.
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• Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition
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