Between-trial heterogeneity in ARDS research

Between-trial heterogeneity in ARDS research

Purpose Most randomized controlled trials (RCTs) in patients with acute respiratory distress syndrome (ARDS) revealed indeterminate or conflicting study results. We aimed to systematically evaluate between-trial heterogeneity in reporting standards and trial outcome. Methods A systematic review of...

Full description

Bibliographic Details
Main Authors:	Juschten, J, Tuinman, PR, Guo, T, Juffermans, NP, Schultz, MJ, Loer, SA, Girbes, ARJ, de Grooth, HJ
Format:	Journal article
Language:	English
Published:	Springer 2021

Similar Items

Incidence, clinical characteristics and outcomes of early hyperbilirubinemia in critically ill patients: insights from the MARS Study
by: Juschten, J, et al.
Published: (2021)

Lung- and diaphragm-protective ventilation by titrating inspiratory support to diaphragm effort: a randomized clinical trial
by: de Vries, HJ, et al.
Published: (2022)

A structured diagnostic algorithm for patients with ARDS
by: Lieuwe Durk Jacobus Bos, et al.
Published: (2023-03-01)

Antithrombin plus alpha-1 protease inhibitor does not affect coagulation and inflammation in two murine models of acute lung injury
by: Jenny Juschten, et al.
Published: (2019-07-01)

Consensus statements on the utility of defining ARDS and the utility of past and current definitions of ARDS—protocol for a Delphi study
by: Nasa, P, et al.
Published: (2024)

Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats
by: Jenny Juschten, et al.
Published: (2020-12-01)

The impact of lung ultrasound on clinical-decision making across departments: a systematic review
by: Heldeweg, MLA, et al.
Published: (2022)

ARDS: challenges in patient care and frontiers in research
by: Lieuwe D. Bos, et al.
Published: (2018-01-01)

ARDS Subphenotypes: Understanding a Heterogeneous Syndrome
by: Jennifer G. Wilson, et al.
Published: (2020-03-01)

Association between early cumulative fluid balance and successful liberation from invasive ventilation in COVID-19 ARDS patients — insights from the PRoVENT-COVID study: a national, multicenter, observational cohort analysis
by: Sanchit Ahuja, et al.
Published: (2022-06-01)

Efficacy and safety of intravenous imatinib in COVID-19 ARDS: a randomized, double-blind, placebo-controlled clinical trial
by: Leila N. Atmowihardjo, et al.
Published: (2023-06-01)

The diagnostic accuracy of lung ultrasound to determine PiCCO-derived extravascular lung water in invasively ventilated patients with COVID-19 ARDS
by: Leila N. Atmowihardjo, et al.
Published: (2023-10-01)

RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial
by: Algera, A, et al.
Published: (2018)

Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup
by: Huikang Xu, et al.
Published: (2023-11-01)

Myocardial function during ventilation with lower versus higher positive end-expiratory pressure in patients without ARDS
by: Algera, AG, et al.
Published: (2022)

Breathing variability—implications for anaesthesiology and intensive care
by: Oscar F. C. van den Bosch, et al.
Published: (2021-08-01)

Ard Burdjan or Ard Dobrudjan? [In Bulgarian]
by: J. Tabov
Published: (2014-12-01)

Arde
by: Gabriel Kessler
Published: (2019-05-01)

ARDS
by: Pramila Bajaj
Published: (2007-01-01)

Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory Distress Syndrome (ARDS): Insights from mathematical modelling
by: Sonu Subudhi, et al.
Published: (2022-01-01)

The INVENT COVID trial: a structured protocol for a randomized controlled trial investigating the efficacy and safety of intravenous imatinib mesylate (Impentri®) in subjects with acute respiratory distress syndrome induced by COVID-19
by: Atmowihardjo, L, et al.
Published: (2022)

Personalized mechanical ventilation guided by ultrasound in patients with acute respiratory distress syndrome (PEGASUS): study protocol for an international randomized clinical trial
by: Sinnige, JS, et al.
Published: (2024)

RELAx – REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial
by: Anna Geke Algera, et al.
Published: (2018-05-01)

Fluids in ARDS: more pros than cons
by: Renata de S. Mendes, et al.
Published: (2020-12-01)

Corticosteroids in ARDS
by: Emmanuelle Kuperminc, et al.
Published: (2023-05-01)

Mortality associated with early changes in ARDS severity in COVID–19 patients – Insights from the PRoVENT–COVID study
by: Schuijt, MTU, et al.
Published: (2021)

Epidemiology, ventilation management and outcomes of COVID–19 ARDS patients versus patients with ARDS due to pneumonia in the Pre–COVID era
by: van der Ven, FLIM, et al.
Published: (2024)

Systems Biology ARDS Research with a Focus on Metabolomics
by: Sayed M. Metwaly, et al.
Published: (2020-05-01)

Use of ECMO in ARDS: does the EOLIA trial really help?
by: Luciano Gattinoni, et al.
Published: (2018-07-01)

How to reduce cisatracurium consumption in ARDS patients: the TOF-ARDS study
by: Sami Hraiech, et al.
Published: (2017-08-01)

Physiological and clinical variables identify ARDS classes and therapeutic heterogeneity to glucocorticoids: a retrospective study
by: Qingbo Liao, et al.
Published: (2023-03-01)

Effects of inspiratory flow on lung stress, pendelluft, and ventilation heterogeneity in ARDS: a physiological study
by: Alessandro Santini, et al.
Published: (2019-11-01)

Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials
by: Shalini Santhakumaran, et al.
Published: (2019-05-01)

Time in (Ard-Alkarab)
by: Adnan Kalid
Published: (1985-12-01)

Regional physiology of ARDS
by: Luciano Gattinoni, et al.
Published: (2017-12-01)

Myocardial Function during Ventilation with Lower versus Higher Positive End-Expiratory Pressure in Patients without ARDS
by: Anna Geke Algera, et al.
Published: (2022-04-01)

Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS
by: Morales-Quinteros, L, et al.
Published: (2021)

The prognostic value of early measures of the ventilatory ratio in the ARDS ROSE trial
by: Ana Carolina Costa Monteiro, et al.
Published: (2022-09-01)

Cardiovascular Subphenotypes in ARDS: Diagnostic and Therapeutic Implications and Overlap with Other ARDS Subphenotypes
by: Minesh Chotalia, et al.
Published: (2023-05-01)

Continuous postoperative pericardial flushing reduces postoperative bleeding after coronary artery bypass grafting: a randomized trial
by: Diephuis, EC, et al.
Published: (2020)