Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia.

Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia.

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Genome-wide array approaches and sequencing analyses are powerful tools for identifying genetic aberrations in cancers, including leukemias and lymphomas. However, the clinical and biological significance of such aberrations and their subclonal distribution are poorly understood. Here, we present th...

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Bibliografiske detaljer
Main Authors:	Knight, S, Yau, C, Clifford, R, Timbs, A, Sadighi Akha, E, Dréau, H, Burns, A, Ciria, C, Oscier, D, Pettitt, A, Dutton, S, Holmes, C, Taylor, J, Cazier, J, Schuh, A
Format:	Journal article
Sprog:	English
Udgivet:	2012

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