Structure and functional characterization of the atypical human kinase haspin.
The protein kinase haspin/Gsg2 plays an important role in mitosis, where it specifically phosphorylates Thr-3 in histone H3 (H3T3). Its protein sequence is only weakly homologous to other protein kinases and lacks the highly conserved motifs normally required for kinase activity. Here we report stru...
Egile Nagusiak: | Eswaran, J, Patnaik, D, Filippakopoulos, P, Wang, F, Stein, R, Murray, J, Higgins, J, Knapp, S |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2009
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