Virus-specific cytotoxic T lymphocytes differentially express cell-surface leukocyte immunoglobulin-like receptor-1, an inhibitory receptor for class I major histocompatibility complex molecules.

Leukocyte immunoglobulin-like receptor-1 (LIR-1) is an inhibitory receptor that negatively regulates T cell effector functions after interaction with host class I major histocompatibility complex molecules and, additionally, binds to UL18, a human cytomegalovirus (HCMV)-encoded class I homologue. He...

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Main Authors: Antrobus, R, Khan, N, Hislop, A, Montamat-Sicotte, D, Garner, L, Rickinson, AB, Moss, P, Willcox, B
格式: Journal article
语言:English
出版: 2005