Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H.

Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H.

We report a patient with peripheral rheumatoid corneal melting who developed a corneal perforation in one eye requiring tectonic keratoplasty. Nine consecutive corneal grafts were rapidly destroyed despite systemic immunosuppression with corticosteroid, cyclophosphamide, azathioprine and cyclosporin...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Newman, D, Isaacs, J, Watson, P, Meyer, P, Hale, G, Waldmann, H
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	1995

Ижил төстэй зүйлс

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Availability of Campath-1 antibodies for bone marrow transplantation.
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Campath-1H therapy in refractory ocular inflammatory disease.
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T-CELL DEPLETION BY EXPOSURE TO CAMPATH-1G IN-VITRO PREVENTS GRAFT-VERSUS-HOST DISEASE
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-н: Hale, G, зэрэг
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Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases.
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CAMPATH: from concept to clinic.
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Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL).
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-н: Heit, W, зэрэг
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In vivo use of Campath-1G to prevent graft-versus-host disease and graft rejection after bone marrow transplantation.
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