The influence of catalysis on mad2 activation dynamics.
Mad2 is a key component of the spindle assembly checkpoint, a safety device ensuring faithful sister chromatid separation in mitosis. The target of Mad2 is Cdc20, an activator of the anaphase-promoting complex/cyclosome (APC/C). Mad2 binding to Cdc20 is a complex reaction that entails the conformati...
Главные авторы: | Simonetta, M, Manzoni, R, Mosca, R, Mapelli, M, Massimiliano, L, Vink, M, Novak, B, Musacchio, A, Ciliberto, A |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2009
|
Схожие документы
-
The influence of catalysis on Mad2 activation dynamics
по: Simonetta, M, и др.
Опубликовано: (2009) -
The influence of catalysis on mad2 activation dynamics.
по: Marco Simonetta, и др.
Опубликовано: (2009-01-01) -
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.
по: Sironi, L, и др.
Опубликовано: (2002) -
Closing the Mad2 cycle
по: Andrea Musacchio
Опубликовано: (2015-05-01) -
MAD or MADness?
по: Francesco Fulvio Faletra, и др.
Опубликовано: (2025-02-01)