Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia

Macrophages are key target cells of Zika virus (ZIKV) infection, implicated as a viral reservoir seeding sanctuary sites such as the central nervous system and testes. This rests on the apparent ability of macrophages to sustain ZIKV replication without experiencing cytopathic effects. ZIKV infectio...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Hanrath, AT, Hatton, CF, Gothe, F, Browne, C, Vowles, J, Leary, P, Cockell, SJ, Cowley, SA, James, WS, Hambleton, S, Duncan, CJA
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Frontiers Media 2022