Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia

Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia

Macrophages are key target cells of Zika virus (ZIKV) infection, implicated as a viral reservoir seeding sanctuary sites such as the central nervous system and testes. This rests on the apparent ability of macrophages to sustain ZIKV replication without experiencing cytopathic effects. ZIKV infectio...

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Bibliographic Details
Main Authors:	Hanrath, AT, Hatton, CF, Gothe, F, Browne, C, Vowles, J, Leary, P, Cockell, SJ, Cowley, SA, James, WS, Hambleton, S, Duncan, CJA
Format:	Journal article
Language:	English
Published:	Frontiers Media 2022

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