Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients: the R4-RA RCT

Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients: the R4-RA RCT

<p><strong>Background</strong></p> Although biological therapies have transformed the outlook for those with rheumatoid arthritis, there is a lack of any meaningful response in approximately 40% of patients. The role of B cells in rheumatoid arthritis pathogenesis is well rec...

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Main Authors: Humby, F, Durez, P, Buch, MH, Lewis, MJ, Bombardieri, M, John, C, Rizvi, H, Warren, L, Peel, J, Fossati-Jimack, L, Hands, RE, Giorli, G, Rivellese, F, Cañete, JD, Taylor, PC, Sasieni, P, Fonseca, JE, Choy, E, Pitzalis, C
Format: Journal article
Language:English
Published: NIHR Journals Library 2022

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