Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation

Understanding medium spiny neuron (MSN) physiology is essential to understand motor impairments in Parkinson's disease (PD) given the architecture of the basal ganglia. Here, we developed a custom three-chambered microfluidic platform and established a cortico-striato-nigral microcircuit partia...

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Bibliographic Details
Main Authors:	Do, QB, Noor, H, Marquez-Gomez, R, Cramb, KML, Ng, B, Abbey, A, Ibarra-Aizpurua, N, Caiazza, MC, Sharifi, P, Lang, C, Beccano-Kelly, D, Baleriola, J, Bengoa-Vergniory, N, Wade-Martins, R
Format:	Journal article
Language:	English
Published:	Springer Nature 2024

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