A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors. The predominant expression of a single cytoadherent PfEMP1 type...
Váldodahkkit: | Kyes, SA, Christodoulou, Z, Raza, A, Horrocks, P, Pinches, R, Rowe, J, Newbold, C |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2003
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Geahča maid
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Transcription of subtelomerically located var gene variant in Plasmodium falciparum appears to require the truncation of an adjacent var gene.
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Plasmodium falciparum var gene expression is developmentally controlled at the level of RNA polymerase II-mediated transcription initiation.
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Stage-specific merozoite surface protein 2 antisense transcripts in Plasmodium falciparum.
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