A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.

The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors. The predominant expression of a single cytoadherent PfEMP1 type...

Full description

Bibliographic Details
Main Authors:	Kyes, SA, Christodoulou, Z, Raza, A, Horrocks, P, Pinches, R, Rowe, J, Newbold, C
Format:	Journal article
Language:	English
Published:	2003

Similar Items

Transcription of subtelomerically located var gene variant in Plasmodium falciparum appears to require the truncation of an adjacent var gene.
by: Horrocks, P, et al.
Published: (2004)

Effect of var gene disruption on switching in Plasmodium falciparum.
by: Horrocks, P, et al.
Published: (2002)

Plasmodium falciparum var gene expression is developmentally controlled at the level of RNA polymerase II-mediated transcription initiation.
by: Kyes, S, et al.
Published: (2007)

A simple RNA analysis method shows var and rif multigene family expression patterns in Plasmodium falciparum.
by: Kyes, S, et al.
Published: (2000)

Stage-specific merozoite surface protein 2 antisense transcripts in Plasmodium falciparum.
by: Kyes, S, et al.
Published: (2002)

Variable var transition rates underlie antigenic variation in malaria.
by: Horrocks, P, et al.
Published: (2004)

Var gene diversity in Plasmodium falciparum is generated by frequent recombination events.
by: Taylor, H, et al.
Published: (2000)

PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes.
by: Horrocks, P, et al.
Published: (2005)

The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria
by: Noble, R, et al.
Published: (2013)

The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria
by: Robert Noble, et al.
Published: (2013-09-01)

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.
by: Recker, M, et al.
Published: (2011)

Stage-specific promoter activity from stably maintained episomes in Plasmodium falciparum.
by: Horrocks, P, et al.
Published: (2002)

Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.
by: Kraemer, S, et al.
Published: (2007)

An approach to classifying sequence tags sampled from Plasmodium falciparum var genes.
by: Bull, P, et al.
Published: (2007)

Rifins: a second family of clonally variant proteins expressed on the surface of red cells infected with Plasmodium falciparum.
by: Kyes, SA, et al.
Published: (1999)

Genomic representation of var gene sequences in Plasmodium falciparum field isolates from different geographic regions.
by: Kyes, S, et al.
Published: (1997)

Febrile temperatures induce cytoadherence of ring-stage Plasmodium falciparum-infected erythrocytes.
by: Udomsangpetch, R, et al.
Published: (2002)

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.
by: Mario Recker, et al.
Published: (2011-03-01)

Cytoadherence, pathogenesis and the infected red cell surface in Plasmodium falciparum.
by: Newbold, C, et al.
Published: (1999)

Plasmodium falciparum: Pathogenesis, polymorphism and the infected red cell surface
by: Newbold, C, et al.
Published: (1999)

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum.
by: Mourier, T, et al.
Published: (2008)

Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation.
by: Lemieux, J, et al.
Published: (2013)

Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture.
by: Lemieux, J, et al.
Published: (2009)

Genomic representation of var gene sequences in Plasmodium falciparum field isolates from different geographic regions (vol 87, pg 235, 1997)
by: Kyes, S, et al.
Published: (1998)

Variant antigens and endothelial receptor adhesion in Plasmodium falciparum.
by: Gardner, J, et al.
Published: (1996)

A study of var gene transcription in vitro using universal var gene primers.
by: Taylor, H, et al.
Published: (2000)

Genetic restriction of Plasmodium falciparum in an area of stable transmission: an example of island evolution?
by: Maitland, K, et al.
Published: (2000)

Patterns of gene recombination shape <it>var </it>gene repertoires in <it>Plasmodium falciparum: </it>comparisons of geographically diverse isolates
by: Levin Emily, et al.
Published: (2007-02-01)

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes.
by: Smith, J, et al.
Published: (1995)

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria
by: Newbold, C, et al.
Published: (2005)

Plasmodium falciparum: a method for the amplification of S antigens and its application to laboratory and field samples.
by: Kyes, S, et al.
Published: (1993)

Intraerythrocytic polyubiquitin expression in Plasmodium falciparum is subjected to developmental and heat-shock control.
by: Horrocks, P, et al.
Published: (2000)

Identification of a conserved var gene in different Plasmodium falciparum strains
by: Sandra Dimonte, et al.
Published: (2020-05-01)

Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein I
by: Mackintosh, C, et al.
Published: (2008)

Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.
by: Mackintosh, C, et al.
Published: (2008)

Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks.
by: Bull, P, et al.
Published: (2008)

Analysis of adhesive domains from the A4VAR Plasmodium falciparum erythrocyte membrane protein-1 identifies a CD36 binding domain.
by: Smith, J, et al.
Published: (1998)

QUININE INHIBITS CATION-SELECTIVE MEMBRANE-TRANSPORT IN PLASMODIUM-FALCIPARUM-INFECTED HUMAN RED-CELLS
by: Elford, B, et al.
Published: (1990)

Plasmodium falciparum: the human agglutinating antibody response to the infected red cell surface is predominantly variant specific.
by: Newbold, C, et al.
Published: (1992)

Recombination patterns in var gene repertoires of P-falciparum
by: Kraemer, S, et al.
Published: (2006)