Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level.
Failure of the adaptive immune response to control infection with the hepatitis C virus (HCV) can result from mutational escape in targeted T-cell epitopes. Recent studies suggest that T-cell immune pressure is an important factor in the evolution of the nonstructural proteins in HCV. The aim of thi...
Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2008
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Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level
Publicado em 2011
Journal article