Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma

Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma

Multiple myeloma is a genetically heterogeneous cancer of the bone marrow plasma cells (PC). Distinct myeloma transcriptome profiles are primarily driven by myeloma initiating events (MIE) and converge into a mutually exclusive overexpression of the CCND1 and CCND2 oncogenes. Here, with reference to...

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Autors principals:	Alvarez-Benayas, J, Trasanidis, N, Katsarou, A, Ponnusamy, K, Chaidos, A, May, PC, Xiao, X, Bua, M, Atta, M, Roberts, IAG, Auner, HW, Hatjiharissi, E, Papaioannou, M, Caputo, VS, Sudbery, IM, Karadimitris, A
Format:	Journal article
Idioma:	English
Publicat:	Springer Nature 2021

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